L-VALINE PRODUCTION USING MICROBIAL AUXOTROPH
نویسندگان
چکیده
منابع مشابه
L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.
Corynebacterium glutamicum was engineered for the production of L-valine from glucose by deletion of the aceE gene encoding the E1p enzyme of the pyruvate dehydrogenase complex and additional overexpression of the ilvBNCE genes encoding the L-valine biosynthetic enzymes acetohydroxyacid synthase, isomeroreductase, and transaminase B. In the absence of cellular growth, C. glutamicum DeltaaceE sh...
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The molecular structure of (I) is shown in Fig. 1. Bond lengths and angles are normal, but the unusual non-planarity of the peptide bond is quite evident. The associated torsion angle C1ÐC3ÐN2ÐC4 (!) is 157.37 (15) , a deviation from 180 that is superceded among small chiral peptides only by the 156.6 ! angle in N-(tert-butoxycarbonyl)-l-Pro-l-Leu benzyl ester (Sugino et al., 1978). Fig. 2(a) s...
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ژورنال
عنوان ژورنال: The Journal of General and Applied Microbiology
سال: 1961
ISSN: 1349-8037,0022-1260
DOI: 10.2323/jgam.7.52